What is a “CARRIER” of a RECESSIVE Disease?

“Recessive inherited diseases are those in which an individual must inherit TWO COPIES of a mutated gene (one from each parent) in order to develop the associated condition.”

“Dogs inheriting ONE COPY of the mutation from a single parent are considered “Carriers” of the disease and will NOT develop clinical signs of the disease themselves.”

“Therefore, in general, it is recommended to only breed a CARRIER to a dog that is CLEAR of the mutation. Using statistics as a guide, this strategy is expected to result in a litter consisting of approximately 50% carrier offspring and 50% normal or “CLEAR” offspring. Thus, avoiding the removal of the carrier dog and its unique combination of genetic variants that contribute to the overall genetic DIVERSITY of the breed while limiting the number of puppies born with the known, disease-associated mutation.”


“Recessive diseases are particularly troubling for breeders because dogs inheriting a single copy of a disease-causing mutation (“CARRIERS”) do NOT show signs of the disease, But can produce puppies with the disease IF bred to Another Carrier of the Same Mutation. When it comes to genetic diseases, Ben Franklin had it right when he stated, “AN OUNCE OF PREVENTION IS WORTH A POUND OF CURE”.


“In a perfect world in which every dog breeder performed genetic disease testing on their breeding stock and made selective breeding decisions using these results, diseases caused by over 200 known canine genetic mutations could be completely prevented”


https://www.pawprintgenetics.com/products/breeds/39/


* WE DO NOT BREED ANY DOGS WITH TWO COPIES OF A DISEASE. MOST OF OUR DOGS ARE FULL PANEL CLEAR BUT SOME ARE ONLY RECESSIVE CARRIERS.


WE CHOSE TO HAVE A COUPLE OF CARRIERS BECAUSE OF THEIR OTHER AMAZING QUALITIES THEY POSSESS AND THE DIVERSITY THEY BRING TO OUR PROGRAM. 🥰


** WE FULL PANEL GENETIC TEST ALL OF OUR DOGS DESPITE KNOWING THEIR PARENTS ARE TESTED AND WE GUARANTEE OUR PUPPIES WILL NOT BE IMPACTED BY ANY OF THE TEN GENETIC DISEASES WE TEST FOR 🥰


An Example of a Full Panel CLEAR Test Result Page:



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PLACERVILLE, CA 95667
 



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